aromatase
Noun
Meaning
English Wikipedia has an article on:aromataseWikipedia
aromatase (countable and uncountable, plural aromatases)
(biochemistry) An enzyme responsible for aromatization of androgen hormones into estrogens.
Synonyms
Examples
Approximately 0.3% of testosterone is converted into estradiol by aromatase (CYP19A1) citation an enzyme expressed in the brain, liver, and adipose tissues.
Neurons of the oSDN show aromatase expression which is also smaller in male-oriented rams versus female-oriented rams, suggesting that sexual orientation is neurologically hard-wired and may be influenced by hormones.
In studies using genetic knock-out techniques in inbred mice, male mice that lacked a functional aromatase enzyme displayed a marked reduction in aggression.
Estrogen secreting adrenaocarcinoma in an 18-month-old boy: aromatase activity, protein expression, mRNA and utilization of gonadal type promoter.
Then in 1995, Swaab et al. citation linked brain development to sexual orientation by treating male rats both pre- and postnatally with ATD, an aromatase blocker in the brain.
When estrogen levels were raised through the increased activity of the enzyme aromatase in male lab mice, OCD rituals were dramatically decreased.