bioavailability

Noun

Meaning

bioavailability (countable and uncountable, plural bioavailabilities)

(biology, medicine) The extent to which a substance is molecularly available to cells and tissues in a living organism, which depends on factors such as solubility, pH level, and presence of enzymes and cofactors; for example, even if one's ingestion of vitamin B₁₂ is average/typical, one might nonetheless have B₁₂ deficiency if one has poor metabolism of this particular vitamin.
(pharmacology, nutrition) The amount of drug or nutrient which reaches the site of physiological activity after administration.
poor/low oral bioavailability

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Related terms

Examples

A cooking technique called nixtamalization increases the bioavailability of niacin during maize meal/flour production. Source: Internet

Absolute bioavailability has been estimated to be between 64% and 90%. Source: Internet

For example, cooked spinach has a 5% bioavailability of phylloquinone, however, fat added to it increases bioavailability to 13% due to the increased solubility of vitamin K in fat. Source: Internet

Based on these studies, biotin bioavailability may be low or variable, depending on the type of food being consumed. Source: Internet

Carotenoid bioavailability ranges between 1/5 to 1/10 of retinol's. Source: Internet

Grapefruit juice raises the bioavailability of carbamazepine by inhibiting CYP3A4 enzymes in the gut wall and in the liver. Source: Internet

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