clindamycin
Noun
Meaning
clindamycin (uncountable)
(pharmacology) A lincosamide antibiotic drug C18H33ClN2O5S, mostly used to treat infections with anaerobic bacteria.
Synonyms
Examples
In cases of streptococcal toxic shock syndrome, treatment consists of penicillin and clindamycin, given with intravenous immunoglobulin.
Larsson PG, Stray-Pedersen B, Ryttig KR, Larsen S. Human lactobacilli as supplementation of clindamycin to patients with bacterial vaginosis reduce the recurrence rate; a 6-month, double-blind, randomized, placebo-controlled study.
In general, the simultaneous use of two different erythromycin derivatives (such as clindamycin and Mitemcinal ) should be avoided as drugs in this macrolide family possess a common mechanism of action.
If positive, the woman receives IV penicillin or ampicillin while in labor—or, if she is allergic to penicillin, an alternative therapy, such as IV clindamycin or IV vancomycin.
Pollock, p. 77 The resistance to cefoxitin and clindamycin in turn was attributed to Braine's and Hartnell's contact with microorganisms that naturally produce them or random mutation in the chromosomes of Clostridium strains.
The following reactions have been reported with the use of clindamycin.