Cox-2
Noun
Meaning
an enzyme that makes prostaglandins that cause inflammation and pain and fever
Source: WordNetSynonyms
Hypernyms
Examples
the beneficial effects of NSAIDs result from their ability to block Cox-2
Aspirin-modified PTGS2 produces lipoxins, most of which are anti-inflammatory. citation Newer NSAID drugs, COX-2 inhibitors (coxibs), have been developed to inhibit only PTGS2, with the intent to reduce the incidence of gastrointestinal side effects.
COX-1 and COX-2 inhibition At least two different types of cyclooxygenase occur COX-1 and COX-2.
COX-2 inhibitors main These drugs have been derived from NSAIDs.
COX-2 is an enzyme facultatively expressed in inflammation, and it is inhibition of COX-2 that produces the desirable effects of NSAIDs.
COX-1 and COX-2 enzymes may be blocked by pain medications such as Advil and Vioxx in a more complex manner than was previously understood, a Queen's University study has found.