denaturation
Noun
Meaning
The deliberate addition of a noxious substance to alcohol to make it unfit to drink
(biochemistry) The change of folding structure of a protein (and thus of physical properties) caused by heating, changes in pH, or exposure to certain chemicals.
Source: en.wiktionary.orgExamples
This led to the discovery that long chain fatty acids would remarkably stabilize serum albumin to heat denaturation, and would even reverse the denaturation by heat or concentrated urea solutions.
The DNA polymerase isolated from T. aquaticus is stable at high temperatures remaining active even after DNA denaturation, thus obviating the need to add new DNA polymerase after each cycle.
Middle - the fraction of folded and functional enzyme decreases above its denaturation temperature.
The processes of denaturation, annealing and elongation constitute of one cycle.