duloxetine
Noun
Meaning
duloxetine (uncountable)
(pharmacology) A drug that functions as an SNRI and is administered orally in the form of its hydrochloride C18H19NOS·HCl especially to treat depression, anxiety, and chronic pain (such as that associated with fibromyalgia and peripheral neuropathy). It is marketed under the trademark Cymbalta.
Synonyms
Phrases with the word
Examples
Preclinical studies have shown that duloxetine is a potent inhibitor of neuronal and norepinephrine and a less potent inhibitor of reuptake.
In rats, dietary doses of duloxetine up to 27 mg/kg/day in females (2 times the MRHD) and up to 36 mg/kg/day in males (3 times the MRHD) did not increase the incidence of tumors.
Duloxetine : Unlike the other SNRIs listed here duloxetine does not cause dose-dependent hypertension as a common adverse effect.
Serotonin–norepinephrine reuptake inhibitors Serotonin–norepinephrine reuptake inhibitor include venlafaxine and duloxetine drugs.