Hofmann elimination
Noun
Meaning
Hofmann elimination (countable and uncountable, plural Hofmann eliminations)
(chemistry) An elimination reaction of an amine to form alkenes.
Related terms
Examples
The amine or ammonia is not a suitable leaving group, so the amine is first either alkylated (as in the Hofmann elimination ) or oxidized to an amine oxide (the Cope reaction ) to render a smooth elimination possible.