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Hofmann rearrangement

Noun

Meaning

Hofmann rearrangement (plural Hofmann rearrangements)

(chemistry) The organic reaction of a primary amide to a primary amine with one carbon atom less. It involves oxidation of the nitrogen followed by rearrangement of the carbonyl and nitrogen to give an isocyanate intermediate.
Synonym: Hofmann degradation

Source: en.wiktionary.org

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