hydroxylase

Noun

Meaning

hydroxylase (plural hydroxylases)

(biochemistry) Any of several enzymes that catalyze the oxidation of compounds by the introduction of hydroxyl groups.

Phrases with the word

Examples

Both PKU and most non-PKU hyperphenylalaninemia are the result of phenylalanine hydroxylase deficiency (PAHD). Source: Internet

In animals including humans, serotonin is synthesized from the amino acid L - tryptophan by a short metabolic pathway consisting of two enzymes : tryptophan hydroxylase (TPH) and aromatic amino acid decarboxylase (DDC). Source: Internet

Severe diseases such as scurvy can result from defects in this hydroxylation, e.g., mutations in the enzyme prolyl hydroxylase or lack of the necessary ascorbate (vitamin C) cofactor. Source: Internet

Phloretic acid is also a urinary metabolite of tyrosine in rats. citation Ortho- and meta-tyrosine Enzymatic oxidation of tyrosine by phenylalanine hydroxylase (top) and non-enyzmatic oxidation by hydroxyl free radicals (middle and bottom). Source: Internet

Glucocorticoids produced in the adrenal cortex stimulate the synthesis of catecholamines by increasing the levels of tyrosine hydroxylase and PNMT. Source: Internet

Phenylketonuria is caused by absent or virtually absent phenylalanine hydroxylase (PAH) enzyme activity. Source: Internet

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