misfolded

Speech parts

1. misfolded - Adjective

2. misfolded - Verb

Meaning

misfolded

simple past and past participle of misfold

misfolded (comparative more misfolded, superlative most misfolded)

(molecular biology, of a protein or nucleic acid) folded into an incorrect tertiary structure

Examples

Abnormal and or misfolded proteins are degraded more rapidly either due to being targeted for destruction or due to being unstable. Source: Internet

Failure to fold into native structure generally produces inactive proteins, but in some instances misfolded proteins have modified or toxic functionality. Source: Internet

If "overseer" enzymes note that residues are misfolded, proteins within the rER will re-add glucose residues so that other calreticulin/calnexin can bind to these proteins and prevent them from proceeding to the Golgi. Source: Internet

Prions are misfolded proteins that replicate by converting their properly folded counterparts, in their host, to the same misfolded structure they possess. Source: Internet

The misfolded form of TDP-43 forms cytoplasmic inclusions in afflicted neurons, and is found depleted in the nucleus. Source: Internet

They also aid in the lysis and recycling of misfolded proteins that have begun to build up within the cell. Source: Internet

Close letter words and terms