misfolding
Speech parts
1. misfolding - Noun
2. misfolding - Verb
Meaning
misfolding
present participle of misfold
misfolding (plural misfoldings)
An incorrect folding (especially of a protein)
Synonyms
Examples
As in yeast, the prion-like domain of TDP-43 has been shown to be both necessary and sufficient for protein misfolding and aggregation.
In addition, this ER stress may cause the misfolding of protein.
In this way, the prion acts as a template to guide the misfolding of more proteins into prion form.
The misfolding of TDP-43 is largely directed by its prion-like domain.
The project aims to understand protein misfolding and accelerate drug design for disease research.
These mutations promote the misfolding of the proteins into a prion-like conformation.