Noun
N-terminal (plural N-terminals)
Alternative form of N-terminus
In the N-terminal extremity of the catalytic domain there is a glycine -rich stretch of residues in the vicinity of a lysine amino acid, which has been shown to be involved in ATP binding. Source: Internet
In another patient, CAIS was the result of a deficit in the transmission of a transactivating signal from the N-terminal region of the normal androgen receptor to the basal transcription machinery of the cell. Source: Internet
Proteins are often synthesized in an inactive precursor form; typically, an N-terminal or C-terminal segment blocks the active site of the protein, inhibiting its function. Source: Internet
The class C GPCRs are distinguished by their large N-terminal tail, which also contains a ligand-binding domain. Source: Internet
The critical event leading to the activation of p53 is the phosphorylation of its N-terminal domain. Source: Internet
The mechanism of activation is similar to that of PKA: the GEF domain is usually masked by the N-terminal region containing the cAMP binding domain. Source: Internet