N-terminus
Noun
Meaning
N-terminus (plural N-termini)
English Wikipedia has an article on:N-terminusWikipedia
(biochemistry) The end of a polypeptide chain that consists of an amino acid with a free amino group
Synonyms
Related terms
Examples
350px In most, but not all cases, nuclear-encoded chloroplast proteins are translated with a cleavable transit peptide that's added to the N-terminus of the protein precursor.
Sequence specificity Homeodomains can bind both specifically and nonspecifically to B-DNA with the C-terminal recognition helix aligning in the DNA's major groove and the unstructured peptide "tail" at the N-terminus aligning in the minor groove.
Specific amino acid sequences (PTS or peroxisomal targeting signal ) at the C-terminus (PTS1) or N-terminus (PTS2) of peroxisomal matrix proteins signals them to be imported into the organelle.
It is oriented with the N-terminus outside the cell and the C-terminus in the cytosol.
Most chemical synthesis methods proceed from C-terminus to N-terminus, opposite the biological reaction.
Since it is difficult to visualize all the atoms at once, the ribbon shows the rough path of the protein polymer from its N-terminus (blue) to its C-terminus (red).