Noun
nicotinamide (countable and uncountable, plural nicotinamides)
(biochemistry, organic chemistry) The amide of nicotinic acid (or niacin).
ADP-ribosylation of EF-2 is reversed by giving high doses of nicotinamide (a form of vitamin B 3 ), since this is one of the reaction's end-products, and high amounts will drive the reaction in the opposite direction. Source: Internet
However, they require compromises in borderline cases; for example, nicotine contains a pyridine fragment from nicotinamide and pyrrolidine part from ornithine Aniszewski, p. 109 and therefore can be assigned to both classes. Source: Internet
Other forms of vitamin B 3 include the corresponding amide and nicotinamide ("niacinamide"), where the carboxyl group has been replaced by a carboxamide group ( CONHmain ), as well as more complex amides and a variety of esters. Source: Internet
Food sources Nicotinamide occurs in trace amounts mainly in meat, fish, nuts, and mushrooms, as well as to a lesser extent in some vegetables. citation Some countries require fortification with nicotinamide of some foods. Source: Internet
For example, the UK requires fortification of flour and bread with nicotinamide. Source: Internet
High-dose nicotinamide should still, however, be considered as a drug with toxic potential at adult doses in excess of 3 g/day and unsupervised use should be discouraged. Source: Internet