nucleophile

Noun

Meaning

English Wikipedia has an article on:nucleophileWikipedia
nucleophile (plural nucleophiles)

(chemistry) A compound or functional group that is attractive to centres of positive charge, and donates electrons, especially donating an electron pair to an electrophile to form a bond.

Examples

Here, sodium amide is used as the nucleophile yielding 2-aminopyridine. Source: Internet

Halogens While the halogens aren't nucleophilic in their diatomic form (i.e. I 2 is not a nucleophile), their anions are good nucleophiles. Source: Internet

For instance, phosgene is a highly reactive nucleophile acceptor, which makes it an excellent reagent for polymerizing diols and diamines to produce polycarbonate and polyurethane plastics. Source: Internet

It is this deprotonation that allows the serine side chain to act as a nucleophile and bind to the electron-deficient carbonyl carbon of the protein main chain. Source: Internet

Formation of amino acids Glutamine is synthesized from glutamate by glutamine synthetase, which utilizes an ATP to form glutamyl phosphate; this intermediate is attacked by ammonia as a nucleophile giving glutamine and inorganic phosphate. Source: Internet

Joule, p. 130 Nucleophilic substitutions In contrast to benzene, pyridine efficiently supports several nucleophilic substitutions, and is regarded as a good nucleophile ( donor number 33.1). Source: Internet

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