nucleophilic
Adjective
Meaning
nucleophilic (not comparable)
(chemistry) of, or relating to a nucleophile
Antonym: electrophilic
Examples
A monosaccharide can switch from the acyclic (open-chain) form to a cyclic form, through a nucleophilic addition reaction between the carbonyl group and one of the hydroxyls of the same molecule.
Another form of ligand exchange is seen in the nucleophilic abstraction reaction.
However, unlike benzene and its derivatives, pyridine is more prone to nucleophilic substitution and metalation of the ring by strong organometallic bases.
Halogens While the halogens aren't nucleophilic in their diatomic form (i.e. I 2 is not a nucleophile), their anions are good nucleophiles.
First, the 2'OH of a specific branchpoint nucleotide within the intron, defined during spliceosome assembly, performs a nucleophilic attack on the first nucleotide of the intron at the 5' splice site, forming the lariat intermediate.
Catalysis Catalysis is achieved by one of two mechanisms: *Aspartic, glutamic and metallo- proteases activate a water molecule which performs a nucleophilic attack on the peptide bond to hydrolyse it.