nucleosome

Noun

Meaning

English Wikipedia has an article on:nucleosomeWikipedia
nucleosome (plural nucleosomes)

(genetics) Any of the subunits that repeat in chromatin; a coil of DNA surrounding a core of eight histones.

Synonyms

Examples

ATP-dependent nucleosome remodeling A number of distinct reactions are associated with the term ATP-dependent chromatin remodeling. Source: Internet

In addition to the core histones, there is the linker histone, H1, which contacts the exit/entry of the DNA strand on the nucleosome. Source: Internet

H2A can be replaced by H2AZ (which leads to reduced nucleosome stability) or H2AX (which is associated with DNA repair and T cell differentiation), whereas the inactive X chromosomes in mammals are enriched in macroH2A. Source: Internet

However, even in chromosomal regions that were not associated with transcriptional changes, nucleosome repositioning was observed, suggesting that the covering and uncovering of transcriptional DNA does not necessarily produce a transcriptional event. Source: Internet

Asymmetries in the nucleosome core particle at 2.5 A resolution. Source: Internet

In 2012, Beena Pillai's laboratory has demonstrated that nucleosome sliding is one of the possible mechanism for large scale tissue specific expression of genes. Source: Internet

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