centromere
Noun
Meaning
a specialized condensed region of each chromosome that appears during mitosis where the chromatids are held together to form an X shape
Source: WordNetSynonyms
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Examples
the centromere is difficult to sequence
An important reference point along a chromosome is the centromere ; the distance from a gene to the centromere is referred to as the gene's locus or map location.
A kinetochore is a proteinaceous microtubule-binding structure that forms on the chromosomal centromere during late prophase.
In most organisms, constitutive heterochromatin occurs around the chromosome centromere and near telomeres.
DNA sequences are both necessary and sufficient to specify centromere identity and function in organisms with point centromeres.
If the centromere is inherited epigenetically from one generation to the next, the problem is pushed back to the origin of the first metazoans.