oncogene
Noun
Meaning
a gene that disposes normal cells to change into cancerous tumor cells
Source: WordNetSynonyms
Hypernyms
Related terms
Examples
A new study pinpoints the inverse correlation between a known oncogene -- a gene that promotes the development of cancer -- and the expression of an oncosuppressor microRNA as the reason for extended pancreatic cancer survival.
Experiments performed by Dr. G. Steve Martin of the University of California, Berkeley demonstrated that the Src was indeed the oncogene of the virus.
For this discovery, proving Todaro and Heubner's "oncogene theory", Bishop and Varmus were awarded the Nobel Prize in Physiology or Medicine in 1989.
Michael Bishop and Harold Varmus showed that the oncogene of Rous sarcoma virus is in fact not specific to the virus but is contained in the genome of healthy animals of many species.
Oncoproteins are any proteins coded by an oncogene and they play an important role in the regulation or synthesis of proteins linked to tumorigenic cell growth.
The loss of these genes may be even more important than proto-oncogene/ oncogene activation for the formation of many kinds of human cancer cells.