phosphodiester

Noun

Meaning

(biochemistry) any of many biologically active compounds in which two alcohols form ester bonds with phosphate

(biochemistry) any phospholipid, such as lecithin, that has two ester groups

Examples

Single-strand breaks are repaired by DNA ligase using the complementary strand of the double helix as a template, citation with DNA ligase creating the final phosphodiester bond to fully repair the DNA. Source: Internet

Yeast tRNA cyclic phosphodiesterase cleaves the cyclic phosphodiester group to form a 2'-phosphorylated 3' end. Source: Internet

The sugars are joined together by phosphate groups that form phosphodiester bonds between the third and fifth carbon atoms of adjacent sugar rings. Source: Internet

This group makes the molecule less stable because when not constrained in a double helix, the 2' hydroxyl can chemically attack the adjacent phosphodiester bond to cleave the phosphodiester backbone. Source: Internet

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