1. screw up - Noun
2. screw up - Verb
3. screw up - Phrase
make a mess of, destroy or ruin
make more intense
twist into a strained configuration
screw or turn higher
Source: WordNetscrew-up
We need to accept that we won't always make the right decisions, that we'll screw up royally sometimes - understanding that failure is not the opposite of success, it's part of success. Arianna Huffington
Apologize when you screw up and focus on other people, not on yourself. Randy Pausch
If it's over--if it's really over--then don't let it screw up the rest of your life. Nicholas Sparks
Genius or fool, you don't live in the world alone. You can hide underground or you can build a wall around yourself, but somebody's going to come along and screw up the works. Haruki Murakami
Given enough time humans will screw up Wikipedia just as they have screwed up everything else, but so far it's not too bad. Jimmy Wales
Some people go to bed at night thinking, 'That was a good day.' I am one of those who worries and asks, 'How did I screw up today?' Tom Hanks