Noun
a Spanish title or form of address for a married woman; similar to the English `Mrs' or `madam'
Source: WordNetHe raised Colegio de Nuestra Senora del Santisimo Rosario (now University of Santo Tomas ) to a University in November 20, 1645 during his pontificate. Source: Internet
It is currently owned by Senora Isabel del Valle Cram. Source: Internet