Noun
(medicine) Initialism of selective serotonin reuptake inhibitor.
(medicine) Initialism of serotonin-specific reuptake inhibitor.
Source: en.wiktionary.orgA 2006 meta-analysis review found wide variation in the findings of prior studies; for patients who had failed to respond to an SSRI antidepressant, between 12% and 86% showed a response to a new drug. Source: Internet
Also the most toxic SSRI in overdose. Source: Internet
Has the highest affinity of any SSRI towards the sigma-1 receptor at which it serves as an agonist. citation Less hepatotoxic than most other antidepressants. Source: Internet
Due to dextromethorphan's SSRI (selective serotonin re-uptake inhibitor)-like action, the sudden cessation of recreational dosing in tolerant individuals can result in mental and physical withdrawal symptoms similar to the withdrawal from SSRIs. Source: Internet
For this reason a concurrent benzodiazepine is sometimes used temporarily until the anxiolytic effect of the SSRI occurs. Source: Internet
It occurs in about 15% of SSRI overdoses. Source: Internet