thymine
Noun
Meaning
a base found in DNA (but not in RNA) and derived from pyrimidine; pairs with adenine
Source: WordNetSynonyms
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Examples
Adenine pairs with thymine (two hydrogen bonds), and guanine pairs with cytosine (stronger: three hydrogen bonds).
Adenine binds with thymine and uracil; Thymine binds only with adenine; and cytosine and guanine can bind only with one another.
At these points, one primer set recognizes DNA with cytosines to amplify methylated DNA, and one set recognizes DNA with uracil or thymine to amplify unmethylated DNA.
DNA is first treated with sodium bisulfite, which converts unmethylated cytosine bases to uracil, which is recognized by PCR primers as thymine.
Depiction of the adenine thymine Watson-Crick base pair.
Here, purines form hydrogen bonds to pyrimidines, with adenine bonding only to thymine in two hydrogen bonds, and cytosine bonding only to guanine in three hydrogen bonds.