methionine
Noun
Meaning
a crystalline amino acid containing sulfur; found in most proteins and essential for nutrition
Source: WordNetSynonyms
Hypernyms
Phrases with the word
Examples
Aminoglycoside antibiotics used to treat urinary tract infections work best in alkaline conditions, and urinary acidification from using methionine can reduce its effectiveness.
FFI is also invariably linked to the presence of the methionine codon at position 129 of the mutant allele, whereas fCJD is linked to the presence of the valine codon at that position.
Homoserine is the branching point with the threonine pathway, where instead it is isomerised after activating the termainal hydroxyl with phosphate (also used for methionine biosynthesis in plants).
Excluding the few exceptions where methionine may act as a redox sensor (e.g. citation ), methionine residues do not have a catalytic role. citation This is in contrast to cysteine residues, where the thiol group has a catalytic role in many proteins.
Biosynthesis Methionine biosynthesis As an essential amino acid, methionine is not synthesized de novo in humans and other animals, who must ingest methionine or methionine-containing proteins.
Homocysteine can also be remethylated using glycine betaine (NNN-trimethyl glycine, TMG) to methionine via the enzyme betaine-homocysteine methyltransferase (E.